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Protein Coding Gene : Hoxd11 homeobox D11

Primary Identifier  MGI:96203 Organism  mouse, laboratory
Chromosome  2 NCBI Gene Number  15431
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Acts upstream of or within several processes, including embryonic morphogenesis; kidney development; and regionalization. Predicted to be located in nucleoplasm. Predicted to be active in nucleus. Is expressed in several structures, including embryo mesenchyme; genitourinary system; limb; nervous system; and skin. Orthologous to human HOXD11 (homeobox D11).
PHENOTYPE: Homozygotes for targeted null mutations exhibit homeotic transformations of sacral vertebrae, malformations of distal limbs, and reduced fertility in males. [provided by MGI curators]
  • synonyms:
  • MGD-MRK-10861,
  • E230017H14Rik,
  • Hox-5.5,
  • RIKEN cDNA E230017H14 gene,
  • homeo box-4 cluster, gene 6,
  • MGD-MRK-10904,
  • Hox-5.4,
  • MGI:2442499,
  • homeo box-5 cluster, gene 4,
  • Hox-4.6,
  • Hoxd11,
  • MGD-MRK-10853,
  • homeobox D11

Features --> Cross References

Genome

Sequence Feature Displayer

JG Browse Displayer

0 Canonical

0 CDSs

0 Exons

1 Genomic Clusters

38 Involved In Mutations

0 Strain

0 Transcripts

2 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

0 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

2 Driver For