Primary Identifier | IPR016242 | Type | Family |
Short Name | Mps1 |
description | Mps1 is a serine/threonine-protein kinase involved in the phosphorylation of many mitotic regulators. It is required for spindle pole body (SPB) duplication and spindle checkpoint function [, ]. It is involved in sister chromatid biorientation in mitosis and meiosis []. The expression of Mps1 is regulated in a cell cycle-dependent manner, and the activity of Mps1 can be regulated through autophosphorylation []. |