First Author | Rutherford MS | Year | 1993 |
Journal | Genomics | Volume | 18 |
Issue | 3 | Pages | 698-701 |
PubMed ID | 8307580 | Mgi Jnum | J:16168 |
Mgi Id | MGI:64258 | Doi | 10.1016/s0888-7543(05)80377-5 |
Citation | Rutherford MS, et al. (1993) The gene for murine CTP:phosphocholine cytidylyltransferase (Ctpct) is located on mouse chromosome 16. Genomics 18(3):698-701 |
abstractText | CTP:phosphocholine cytidylyltransferase is the rate-controlling enzyme in phosphatidylcholine biosynthesis and is essential for the survival of eukaryotic cells. The murine cDNA for the cytidylyltransferase was cloned and sequenced. A genomic clone was isolated and the chromosomal location of the Ctpct locus determined by Southern blot hybridization of DNAs from a panel of interspecific backcross progeny derived from matings of [(C57BL/6J x Mus spretus)F1 x C57BL/6J] mice. These data place the Ctpct gene on mouse chromosome 16 between the Smst and Stf-1 genes. |