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Allele : TgTn(sb-T2/Onc)68Dla transgenic transposon concatemer 68, David A Largaespada

Primary Identifier  MGI:3612984 Allele Type  Transgenic
Attribute String  Transposon concatemer Gene  TgTn(sb-T2/Onc)68Dla
Strain of Origin  FVB/N Is Recombinase  false
Is Wild Type  false
molecularNote  A concatemer of sleeping beauty transposable elements each consisting of the inverted repeat direct repeat sequence specific for sleeping beauty transposase flanking splice acceptor sites and poly A signals in both orientations. Between the splice acceptor sites is 5' long terminal repeat sequence from the murine stem cell virus followed by a splice donor site. This construct can create both loss-of-function and gain-of-function mutations. In line 68 the concatemer is integrated into chromosome 15. Around 25 copies of the construct are integrated in this line and the construct is unmethylated.
  • mutations:
  • Insertion
  • synonyms:
  • SB LC68,
  • T2/Onc15,
  • SB LC68,
  • T2/Onc15,
  • onc1,
  • onc1
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

2 Carried By

Trail: Allele

0 Driven By

20 Publication categories

Trail: Allele