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Protein Coding Gene : C2 complement C2
Primary Identifier  MGI:88226 Organism  mouse, laboratory
Chromosome  17 NCBI Gene Number  12263
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0)

Predicted to enable metal ion binding activity and serine-type endopeptidase activity. Predicted to be involved in complement activation; positive regulation of apoptotic cell clearance; and response to bacterium. Predicted to act upstream of or within complement activation, classical pathway and innate immune response. Located in extracellular space. Is expressed in several structures, including hemolymphoid system; liver; metanephros; placenta; and yolk sac. Human ortholog(s) of this gene implicated in Alzheimer's disease; age related macular degeneration 14; complement component 2 deficiency; macular degeneration; and psoriasis. Orthologous to human C2 (complement C2).
  • synonyms:
  • C2,
  • MGD-MRK-1699,
  • classical-complement pathway C3/C5 convertase,
  • complement C2
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Features --> Cross References

Genome

Sequence Feature Displayer

JG Browse Displayer

0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

0 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

6 Pathways

Trail: ProteinCodingGene

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For





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