Primary Identifier | MGI:5563794 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Mir128-1 |
Transmission | Germline | Strain of Origin | B6(Cg)-Tyr<c-2J> |
Is Recombinase | false | Is Wild Type | false |
molecularNote | A loxP site and an FRT flanked neo cassette were inserted upstream of the microRNA region and a loxP site was inserted downstream of the region. Recombinase mediated recombination removed the neo cassette and the microRNA coding region. Expression of Mir128 was reduced by 20% in the brain of homozygous mice. |