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Allele : Bmpr1a<tm2.1Bhr> bone morphogenetic protein receptor, type 1A; targeted mutation 2.1, Richard R Behringer

Primary Identifier  MGI:2158390 Allele Type  Targeted
Attribute String  Conditional ready, No functional change Gene  Bmpr1a
Transmission  Germline Strain of Origin  129S7/SvEvBrd-Hprt1<+>
Is Recombinase  false Is Wild Type  false
molecularNote  Homologous recombination introduced a floxed neomycin resistance cassette into intron 2, and a single loxP site into intron 1. Cre-mediated recombination in vivo under the control of a CMV promoter excised the neo cassette in the germline, leaving single loxP sites flanking exon 2, which encodes roughly a third of the extracellular domain of the receptor within the ligand-binding domain.
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • ALK3<F>,
  • Bmpr1a<fx(exon2)>,
  • Bmpr1a fl,
  • Bmpr1a<fl>,
  • Bmpr1a<fx(exon2)>,
  • Bmpr1a<fx>,
  • Bmpr1a<fx>,
  • Bmpr1a fx,
  • floxP,
  • Bmpr1a<f>,
  • BmpRIA<flox>,
  • Bmpr1a<f>,
  • ALK3<F>,
  • Bmpr1a fl,
  • Bmpr1a<tm1.1Cren>,
  • Bmpr1a<fl>,
  • floxP,
  • Alk3<flox>,
  • Alk3<flox>,
  • BmpRIA<flox>,
  • Bmpr1a fx,
  • Bmpr1a<tm1.1Cren>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

3 Carried By

Trail: Allele

0 Driven By

184 Publication categories

Trail: Allele