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Protein Coding Gene : Smc1b structural maintenance of chromosomes 1B
Primary Identifier  MGI:2154049 Organism  mouse, laboratory
Chromosome  15 NCBI Gene Number  140557
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Enables DNA binding activity. Acts upstream of or within meiotic cell cycle and sister chromatid cohesion. Located in chromosome, centromeric region and lateral element. Part of meiotic cohesin complex. Is expressed in gonad; ovary; primary spermatocyte; and testis. Orthologous to human SMC1B (structural maintenance of chromosomes 1B).
PHENOTYPE: Homozygous mutant mice display male and female infertility, abnormal male and female meiosis, and arrest of spematogenesis. [provided by MGI curators]
  • synonyms:
  • Smc1b,
  • structural maintenance of chromosomes 1B,
  • SMC1beta,
  • Smc1l2,
  • SMC (structural maintenace of chromosomes 1)-like 2 (S. cerevisiae)
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3 Involved In Mutations

Trail: ProteinCodingGene

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Trail: ProteinCodingGene




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