| Primary Identifier | MGI:2680317 | Allele Type | Targeted |
| Attribute String | Humanized sequence | Gene | Gba1 |
| Transmission | Germline | Strain of Origin | 129S5/SvEvBrd |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | A loxP site flanked neomycin resistance gene was inserted into intron 8 and an A-to-G point mutation was created at position 1249 (GenBank M24119) in exon 9 causing an N-to-S amino acid substitution at residue 388 (370 in mature protein) (p.N388S). The neo cassette was then removed through subsequent Cre-mediated recombination. |
