Primary Identifier | MGI:1919161 | Organism | mouse, laboratory |
Chromosome | 16 | NCBI Gene Number | 71911 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0) Predicted to enable 3-hydroxybutyrate dehydrogenase activity and phospholipid binding activity. Predicted to be involved in steroid metabolic process. Predicted to act upstream of or within lipid metabolic process. Located in mitochondrial inner membrane. Is expressed in several structures, including alimentary system; genitourinary system; integumental system; nervous system; and sensory organ. Orthologous to human BDH1 (3-hydroxybutyrate dehydrogenase 1). PHENOTYPE: Mice homozygous for a conditional allele activated in cardiac cells exhibit partial postnatal lethality and increased heart failure following fasting or TAC/MI. [provided by MGI curators] |