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Comment :

Type  MGI:General Description  early embryo demise and failure of implantation increased number of 1-cell embryos, indicating a lag in the progression from the 1-cell to 2-cell stage at E1.5 less normal appearing 8-cell stage embryos, increased number of 2- and 4-cell embryos at E2.5 no morphologically normal blastocysts, only 4 and 8 cell stage embryos at E3.5