Primary Identifier | MGI:2180119 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Adcyap1r1 |
Transmission | Germline | Strain of Origin | 129P2/OlaHsd |
Is Recombinase | false | Is Wild Type | false |
molecularNote | ES cells were transfected with a construct in which a LoxP site was inserted just upstream of exon 11 and a floxed neomycin-thymidine-kinase region inserted downstream. The transient expression of cre recombinase in ES cells resulted in the excision of the selection genes and exon 11, which encodes a portion of the transmembrane domain IV and is included in all known splice variants. |