| Primary Identifier | IPR037818 | Type | Family |
| Short Name | TAF8 |
| description | Transcription initiation factor TFIID subunit 8 (TAF8 or TAF(II)65) is a component of the general purpose transcription factor complex TFIID [, ]. TAF8 contains a histone fold domain []. This entry includes TAF8 from animals, plants and fungi.The DNA-binding general transcription factor complex TFIID is central to the initiation of DNA-dependent RNA polymerase II transcription. TFIID is the only general transcription initiation factor that bind to the TATA box. The binding of TFIID to the TATA-box is the first step in the formation of a complex able to initiate transcription []. TFIID consists of the TATA binding protein (TBP) and 14 TBP-associated factors (TAFs). One copy of each TAF1, TAF2, TAF3, TAF7, TAF8, TAF11, TAF13, two copies of each TAF4, TAF5, TAF6, TAF9, TAF10, TAF12, and three copies of TAF14 []. |
