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Allele : Tg(Myh6*-mCherry)2Mik transgene insertion 2, Michael I Kotlikoff
Primary Identifier  MGI:5475556 Allele Type  Transgenic
Attribute String  Reporter Gene  Tg(Myh6*-mCherry)2Mik
Strain of Origin  (C57BL/6J x DBA/2NCrl)F2 Is Recombinase  false
Is Wild Type  false
molecularNote  The alpha-MHC-mCherry transgene contains a cardiac-specific alpha myosin heavy-chain (Myh6) mouse promoter sequence upstream of an mCherry fluorescent protein cDNA sequence. The modified mouse Myh6 promoter sequence is minimally active/attenuated through the ablation of three GATA sites and two thyroid-like response elements, thereby directing cardiac-specific mCherry expression and decreased background expression. Founder line 2 were found to have extremely bright mCherry fluorescence in the heart at all stages of development.
  • mutations:
  • Insertion
  • synonyms:
  • cardiac mCherry,
  • cardiac mCherry,
  • a-MHC-mCherry,
  • alphaMHC-mCherry,
  • alpha-MHC-mCherry,
  • alpha-MHC-mCherry,
  • aMHC-mCherry,
  • alphaMHC-mCherry,
  • a-MHC-mCherry,
  • aMHC-mCherry
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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Trail: Allele

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9 Publication categories

Trail: Allele




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