| Primary Identifier | MGI:1343489 | Organism | mouse, laboratory |
| Chromosome | 4 | NCBI Gene Number | 17475 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Involved in dendrite development and intracellular protein transport. Acts upstream of or within cell adhesion. Located in several cellular components, including Schmidt-Lanterman incisure; apical plasma membrane; and bicellular tight junction. Part of subapical complex. Is active in synapse. Is expressed in several structures, including central nervous system; early conceptus; olfactory epithelium; and retina. Human ortholog(s) of this gene implicated in hydrocephalus. Orthologous to human MPDZ (multiple PDZ domain crumbs cell polarity complex component). PHENOTYPE: Mutant heterozygous mice are more sensitive to ethanol withdrawal effects and consume less alcohol than controls. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
