| Primary Identifier | MGI:6209481 | Allele Type | Endonuclease-mediated |
| Attribute String | Not Specified | Gene | Crb1 |
| Inheritance Mode | Dominant | Strain of Origin | B6.Cg-Crb1<rd8> Jak3<m1J>/BocJ |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | TALEN targeting of exon 9 for homologous recombination, using the same single stranded oligonucleotides used to generate the rd8+em1Mvw revertant allele but mediated in fertilized oocytes from a different strain, successfully replace the deleted nucleotide (C/G) in the retinal degeneration 8 (rd8) mutation and incorporates 5 synonymous base substitutions inside the TALEN binding regions. |
