| Primary Identifier | MGI:2158762 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | Ptprf |
| Transmission | Germline | Strain of Origin | 129P2/OlaHsd |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | A neomycin resistance cassette replaced the exons encoding the cytoplasmic tyrosine phosphatase domains. Northern blot analyses detected truncated but not wild-type transcripts in several tissues from homozygous mutant 3 month old male mice. Truncated protein was also detected on the surface of homozgyote thymocytes with reduced expression compared to endogenous protein. |
