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Allele : Bad<tm2Meg> BCL2-associated agonist of cell death; targeted mutation 1.1, Michael E Greeberg

Primary Identifier  MGI:3783745 Allele Type  Targeted
Attribute String  Hypomorph Gene  Bad
Transmission  Germline Strain of Origin  129S4/SvJae
Is Recombinase  false Is Wild Type  false
molecularNote  An exon 3 that contains a nucleotide substitution that results in the amino acid substitution of serine with alanine at position 155 (p.S155A) was knocked into the locus. An FRT site flanked neomycin resistance gene cassette was inserted into intron 4. The neo cassette was removed by germ-line, flp-mediated recombination. The mutation prevents phosphoralyzation of residue 155 in the encoded protein.
  • mutations:
  • Insertion,
  • Nucleotide substitutions
  • synonyms:
  • Bad<S155A>,
  • Bad<S155A>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

7 Publication categories

Trail: Allele