Primary Identifier | MGI:2444211 | Organism | mouse, laboratory |
Chromosome | 1 | NCBI Gene Number | 108954 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Enables protein phosphatase regulator activity. Involved in positive regulation of peptidyl-serine dephosphorylation. Acts upstream of or within ER overload response and response to hydrogen peroxide. Part of protein phosphatase type 1 complex. Is expressed in compacted morula and inner cell mass. Orthologous to human PPP1R15B (protein phosphatase 1 regulatory subunit 15B). PHENOTYPE: Mice homozygous for a null allele die within the first day after birth with decreased weight at birth and red blood cell counts. [provided by MGI curators] |