| Primary Identifier | MGI:1913299 | Organism | mouse, laboratory |
| Chromosome | 16 | NCBI Gene Number | 66049 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Acts upstream of or within several processes, including enamel mineralization; locomotor rhythm; and pH reduction. Predicted to be located in nuclear envelope. Predicted to be part of RAVE complex. Predicted to be active in hippocampal mossy fiber to CA3 synapse and presynapse. Is expressed in several structures, including central nervous system; early conceptus; genitourinary system; sensory organ; and spleen. Used to study Kohlschutter-Tonz syndrome. Human ortholog(s) of this gene implicated in Kohlschutter-Tonz syndrome. Orthologous to human ROGDI (rogdi atypical leucine zipper). PHENOTYPE: Mice lacking exons 6-11 exhibit hyperactivity, memory deficits, increased susceptibility to induced seizures, less mature enamel that is hypomineralized, and recapitulate Kohlschutter-Tonz syndrome. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
