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Allele : Scn4a<tm1.1Ljh> sodium channel, voltage-gated, type IV, alpha; targeted mutation 1.1, Lawrence J Hayward

Primary Identifier  MGI:4366146 Allele Type  Targeted
Gene  Scn4a Inheritance Mode  Recessive
Transmission  Germline Strain of Origin  129S4/SvJae
Is Recombinase  false Is Wild Type  false
molecularNote  The targeting vector inserts a missense substitution changing a methionine to a valine at amino acid position 1592 (M1592V) in exon 24 and a loxP flanked neo cassette in intron 23. The neo cassette is removed by transient infection with a Cre recombinase expressing plasmid leaving a single loxP site downstream of exon 23.
  • mutations:
  • Insertion,
  • Nucleotide substitutions
  • synonyms:
  • SCN4a<M1592V>,
  • SCN4a<M1592V>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

4 Carried By

Trail: Allele

0 Driven By

11 Publication categories

Trail: Allele