Primary Identifier | MGI:1859550 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Trim28 |
Inheritance Mode | Recessive | Transmission | Germline |
Strain of Origin | 129S2/SvPas | Is Recombinase | false |
Is Wild Type | false |
molecularNote | Deletion of exons 4-14 of the coding region as follows: A PGK-neomycin cassette flanked by two loxP sites was introduced into intron 3 and a loxP site was introduced into exon 14. Mice positive for the presence of this allele were mated to CMV-Cre transgenic mice to generate mice in which the loxP flanked sequences were deleted. |