| Primary Identifier | MGI:6164022 | Allele Type | Endonuclease-mediated |
| Attribute String | Humanized sequence | Gene | App |
| Strain of Origin | B6(SJL)-Apoe<tm1.1(APOE*4)Adiuj> Trem2<em1Adiuj>/J | Is Recombinase | false |
| Is Wild Type | false |
| molecularNote | CRISPR/Cas9 genome editing methodologies are used to introduce G601R, F606Y, and R609H point mutations into the App gene. G601R corresponds to a GGA to CGA nucleotide change, F606Y represents a TTT to TAT change, and R609H incorporates a CGC to CAT nucleotide change. |
