Primary Identifier | IPR004538 | Type | Family |
Short Name | Haemolysin_A/TlyA |
description | Haemolysins are exotoxins that attack blood cell membranes and cause cell rupture. The mechanism of action is not well defined. Haemolysin A is induced by sodium ribonucleate, and is produced by pathogenic bacterial strains. Haemolysin A from Treponema hyodysenteriae causes swine dysentery []. The homologous protein from Mycobacterium tuberculosis is known as 16S/23S rRNA (cytidine-2'-O)-methyltransferase TlyA and exhibits hemolytic activity in vitro. It catalyses the 2'-O-methylation at nucleotides C1409 in 16S rRNA and C1920 in 23S rRNA [, , ]. |