Primary Identifier | MGI:3586336 | Allele Type | Transgenic |
Attribute String | Inducible, Inserted expressed sequence | Gene | Tg(tetO-Vegfa)90Ala |
Strain of Origin | FVB/N | Induced With | doxycycline/tetracycline |
Is Recombinase | false | Is Wild Type | false |
molecularNote | This transgene contains cDNA for the murine Vegfa isoform VEGF-A164 which was inserted between seven copies of the tetracycline operator (tetO)7-CMV minimal promoter and the bovine growth factor polyadenylation signals sequence. TetO, when present in cells also carrying a tetracycline transactivator (tTA) or reverse transactivator (rtTA) transgene, is inactivated or activated, respectively, by the administration of tetracycline or its analogue doxycycline. |