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Publication : The interplay between neutrophils and microbiota in cancer.

First Author  Smith CK Year  2018
Journal  J Leukoc Biol Volume  104
Issue  4 Pages  701-715
PubMed ID  30044897 Mgi Jnum  J:265983
Mgi Id  MGI:6201801 Doi  10.1002/JLB.4RI0418-151R
Citation  Smith CK, et al. (2018) The interplay between neutrophils and microbiota in cancer. J Leukoc Biol 104(4):701-715
abstractText  The role of the microbiota in many diseases including cancer has gained increasing attention. Paired with this is our expanding appreciation for the heterogeneity of the neutrophil compartment regarding surface marker expression and functionality. In this review, we will discuss the influence of the microbiota on granulopoiesis and consequent activity of neutrophils in cancer. As evidence for this microbiota-neutrophil-cancer axis builds, it exposes new therapeutic targets to improve a cancer patient's outcome.
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