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Allele : Irf5<tm1.1Mrl> interferon regulatory factor 5; targeted mutation 1.1, Merck Research Laboratory
Primary Identifier  MGI:6433825 Allele Type  Targeted
Attribute String  Conditional ready, No functional change Gene  Irf5
Transmission  Germline Strain of Origin  C57BL/6NTac
Is Recombinase  false Is Wild Type  false
molecularNote  Exons 3 to 9 were flanked by loxP sites (size of loxP-flanked region 4.2 kb). A polyadenylation signal (hGHpA: human Growth Hormone polyadenylation signal) has been inserted 3' of the gene in order to prevent downstream transcription. The conditional KO allele was obtained after Flp-mediated removal of the selection marker.
  • mutations:
  • Insertion
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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0 Driven By

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Trail: Allele




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