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Protein Domain : PHD finger protein 20-like

Primary Identifier  IPR043449 Type  Family
Short Name  PHF20-like
description  This entry includes PHF20 and PHF20L1 proteins.PHD finger protein 20 (PHF20) binds dimethyl lysine residues via its Tudor domain []. It is a component of the MLL1, MOF histone acetyltransferase []and NSL protein complexes [].PHF20L1 binds to monomethylated lysine 142 on DNA (cytosine-5) methyltransferase 1 (DNMT1). It has been shown to antagonize DNMT1 proteasomal degradation [].

1 Child Features

0 Parent Features

11 Protein Domain Regions