Primary Identifier | MGI:5521597 | Allele Type | Targeted |
Gene | Gata1 | Transmission | Germline |
Strain of Origin | (129X1/SvJ x 129S1/Sv)F1-Kitl<+> | Is Recombinase | false |
Is Wild Type | false |
molecularNote | Exon 2 was replaced with a modified exon 2 in which nucleotide substitutions (TCA to GAG) result in the amino acid susbtitution of glutamic acid for serine at position 26 (S26E). This mutation mimics phosphorylation at this site. Cre-mediated recombination removed the floxed neomycin resistance cassette inserted downstream of the modified exon 2. |