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Allele : Tg(PRNP-APPSwe)6Dwst transgene insertion 6, David Westaway
Primary Identifier  MGI:3589474 Allele Type  Transgenic
Attribute String  Inserted expressed sequence Gene  Tg(PRNP-APPSwe)6Dwst
Strain of Origin  (C3H/HeJ x C57BL/6J)F1 Is Recombinase  false
Is Wild Type  false
molecularNote  The transgene expresses the mutant human amyloid protein precursor APPSwe, which bears the Swedish (K670N/M671L) mutation, under the control of the Syrian hamster prion protein promoter. Transgenic mice express the App protein in brain at approximately 5 times the level of control mice.
  • mutations:
  • Insertion
  • synonyms:
  • TgCRND6,
  • TgCRND6
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1 Feature

Trail: Allele

Genome

1 Expresses

Trail: Allele

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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Trail: Allele




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