| Primary Identifier | MGI:2386976 | Organism | mouse, laboratory |
| Chromosome | 17 | NCBI Gene Number | 224814 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Predicted to enable ABC-type glutathione S-conjugate transporter activity and ABC-type xenobiotic transporter activity. Predicted to be involved in leukotriene metabolic process; leukotriene transport; and transmembrane transport. Predicted to act upstream of or within lipid transport. Predicted to be located in basolateral plasma membrane. Predicted to be active in membrane. Orthologous to human ABCC10 (ATP binding cassette subfamily C member 10). PHENOTYPE: Mice homzozygous for a knock-out allele exhibit increased sensitivity to paclitaxel-induced mortality associated with weight loss, decreased white blood cell, and small spleen and thymus cortex due to apoptosis and/or depopulation of lymphoid cells. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
