Primary Identifier | MGI:1916185 | Organism | mouse, laboratory |
Chromosome | 1 | NCBI Gene Number | 98685 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0) Predicted to enable S-adenosylmethionine-dependent methyltransferase activity; metal ion binding activity; and tRNA binding activity. Acts upstream of or within adult locomotory behavior. Predicted to be active in nucleus. Is expressed in several structures, including alimentary system; hemolymphoid system gland; male reproductive gland or organ; nervous system; and respiratory system. Orthologous to human TRMT1L (tRNA methyltransferase 1 like). PHENOTYPE: Mice homozygous for a gene trapped allele are viable and anatomically normal but display significantly impaired motor coordination and aberrant exploratory behavior. [provided by MGI curators] |