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Allele : Tnfrsf1a<tm1Gkl> tumor necrosis factor receptor superfamily, member 1a; targeted mutation 1, George Kollias

Primary Identifier  MGI:6448092 Allele Type  Targeted
Attribute String  Null/knockout Gene  Tnfrsf1a
Transmission  Germline Strain of Origin  129S/SvEv-Gpi1<c>
Is Recombinase  false Is Wild Type  false
molecularNote  A targeting vector was designed to delete 15 nucleotides in exon 6 encoding amino acids 202-206. Southern blot and PCR confirmed recombination. Flow cytometry of peritoneal cells indicated that the mutation abolished receptor shedding.
  • mutations:
  • Insertion,
  • Intragenic deletion
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

3 Publication categories

Trail: Allele