| Type | MGI:General | Description | mice from 2 lines (1 and 2) of double transgenic founders die within 2 months postpartum; early mortality can be prevented by repression of MET expression with doxycycline administration to mating parents, and then to pups until 4 weeks of age with this doxycycline treatment, animals appear normal until 10 months of age, then mice start dying mice from 2 other lines (3 and 4) of double transgenic parents are healthy at birth, then begin to die at 4 months of age |
