| Primary Identifier | MGI:1346325 | Organism | mouse, laboratory |
| Chromosome | 13 | NCBI Gene Number | 23882 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Enables identical protein binding activity. Involved in positive regulation of cold-induced thermogenesis. Acts upstream of or within positive regulation of MAPK cascade and regulation of cell cycle. Predicted to be active in cytoplasm and nucleus. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; integumental system; and sensory organ. Orthologous to human GADD45G (growth arrest and DNA damage inducible gamma). PHENOTYPE: Mice homozygous for some null alleles exhibit male to female sex reversal, abnormal T-helper 1 and NK physiology, decreased type IV hypersensitivity, altered cellular survival to osmotic stress and impaired adaptive thermogenesis. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
