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Protein Domain : Transcription factor, GATA-2/3

Primary Identifier  IPR016374 Type  Family
Short Name  TF_GATA-2/3
description  GATA transcription factors mediate processes of development, differentiation, and gene expression in multiple tissues and cell types. Vertebrate GATA factors have two highly conserved zinc finger motifs and recognise a six-nucleotide motif T/AGATAG/A in target genes. They are separated into two subfamilies: 1) GATA1, GATA2, and GATA3 and 2) GATA4, GATA5, and GATA6. Members of the GATA1/2/3 subfamily are expressed in developing blood cells, where they regulate differentiation-specific gene expression in hematopoiesis []. This entry represents the GATA2 and GATA3.

2 Child Features

1 Parent Features

10 Protein Domain Regions