Primary Identifier | IPR028310 | Type | Family |
Short Name | RBL1 |
description | This entry represents the retinoblastoma-like protein 1 (RBL1, also known as p107). Members of this family contain a conserved domain named the 'pocket' that interacts with the LXCXE motif found in viral proteins, such as SV40 large T antigen []. RBL1 is a component of the DREAM complex, which represses cell cycle-dependent genes in quiescent cells and plays a role in the cell cycle-dependent activation of G2/M genes [, ]. |