| Primary Identifier | MGI:102770 | Organism | mouse, laboratory |
| Chromosome | 17 | NCBI Gene Number | 14913 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Enables calcium sensitive guanylate cyclase activator activity. Acts upstream of or within phototransduction and visual perception. Located in cone photoreceptor outer segment and photoreceptor inner segment. Is expressed in central nervous system; early embryo; and eye. Human ortholog(s) of this gene implicated in cone-rod dystrophy 14. Orthologous to human GUCA1A (guanylate cyclase activator 1A). PHENOTYPE: Mice heterozygous or homozygous for a knock-in allele exhibit photoreceptor degeneration and loss of cone and rod function. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
