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Protein Coding Gene : U2af1 U2 small nuclear ribonucleoprotein auxiliary factor (U2AF) 1

Primary Identifier  MGI:98884 Organism  mouse, laboratory
Chromosome  17 NCBI Gene Number  108121
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Enables RS domain binding activity. Predicted to be involved in mRNA splicing, via spliceosome. Predicted to act upstream of or within RNA splicing and mRNA processing. Located in nuclear speck. Is expressed in several structures, including central nervous system; genitourinary system; peripheral nervous system; sensory organ; and skeleton. Orthologous to human U2AF1 (U2 small nuclear RNA auxiliary factor 1).
PHENOTYPE: Mice homozygous for a conditional allele activated upon induction with pIpC exhibit impaired hematopoietic stem cell survival and function. [provided by MGI curators]
  • synonyms:
  • U2 small nuclear ribonucleoprotein auxiliary factor (U2AF) 1,
  • MGD-MRK-15321,
  • 35kDa,
  • U2af1,
  • RIKEN cDNA 2010107D16 gene,
  • MGI:1914284,
  • 2010107D16Rik

Features --> Cross References

Genome

Sequence Feature Displayer

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

2 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

10 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For