| Primary Identifier | MGI:891971 | Organism | mouse, laboratory |
| Chromosome | 12 | NCBI Gene Number | 20700 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Predicted to enable identical protein binding activity; protease binding activity; and serine-type endopeptidase inhibitor activity. Acts upstream of or within protein N-linked glycosylation; response to cytokine; and response to peptide hormone. Located in extracellular region. Is expressed in gut; liver lobe; and renal calyx. Human ortholog(s) of this gene implicated in several diseases, including alpha 1-antitrypsin deficiency; artery disease (multiple); chronic obstructive pulmonary disease (multiple); inflammatory bowel disease (multiple); and liver disease (multiple). Orthologous to human SERPINA1 (serpin family A member 1). PHENOTYPE: Mice homozygous for a knock-out allele die prior to E8.5. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
