| Primary Identifier | MGI:1098667 | Organism | mouse, laboratory |
| Chromosome | 11 | NCBI Gene Number | 11488 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Predicted to enable metalloendopeptidase activity. Involved in behavioral response to acetic acid induced pain; behavioral response to formalin induced pain; and establishment of protein localization. Predicted to be located in cell projection; plasma membrane; and synapse. Is expressed in several structures, including alimentary system; eye; genitourinary system; liver; and nervous system. Orthologous to human ADAM11 (ADAM metallopeptidase domain 11). PHENOTYPE: Mice homozygous for a targeted disruption of this gene are viable and overtly normal but show impaired hippocampus-dependent spatial learning and cerebellum-dependent motor coordination when tested using water maze and rotating rod tasks. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
