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Protein Domain : Xin actin-binding repeat-containing protein 2

Primary Identifier  IPR030107 Type  Family
Short Name  XIRP2
description  Proteins in this family contains Xin repeats, which define anactin-binding motif. In humans two Xin-repeat proteins have been identified, XIRP1 and XIRP2. They are expressed during early developmental stages of cardiac and skeletal muscles []and have an important role in cardiac development and function []. They bind to and stabilise F-actin [].This entry represents XIRP2, also known as Xin-beta. In mouse, it initiates the maturation of the intercalated discs (ICDs)during postnatal heart development [].

0 Child Features

1 Parent Features

14 Protein Domain Regions