| Primary Identifier | MGI:1917176 | Organism | mouse, laboratory |
| Chromosome | 11 | NCBI Gene Number | 69926 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Predicted to enable dynein intermediate chain binding activity; dynein light intermediate chain binding activity; and minus-end-directed microtubule motor activity. Predicted to be involved in cilium movement involved in cell motility and outer dynein arm assembly. Predicted to be located in sperm flagellum. Predicted to be part of outer dynein arm. Predicted to be active in 9+2 motile cilium and axoneme. Used to study spermatogenic failure 39. Human ortholog(s) of this gene implicated in spermatogenic failure 39. Orthologous to human DNAH17 (dynein axonemal heavy chain 17). PHENOTYPE: Mice homozygous for a null allele exhibit oligozoospermia, globozoospermia, and asthenozoospermia associated with abnormal sperm axoneme morphology. Mice homozygolus for a point mutation allele exhibit reduced fertility and abnormal sperm axoneme morphology. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
