| Primary Identifier | MGI:1202403 | Organism | mouse, laboratory |
| Chromosome | 5 | NCBI Gene Number | 231252 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Enables acetylcholine-gated monoatomic cation-selective channel activity. Involved in membrane depolarization and response to auditory stimulus. Acts upstream of or within several processes, including detection of mechanical stimulus involved in sensory perception of sound; excitatory postsynaptic potential; and inner ear morphogenesis. Predicted to be part of acetylcholine-gated channel complex. Predicted to be active in cholinergic synapse; neuron projection; and postsynaptic specialization membrane. Is expressed in brain. Human ortholog(s) of this gene implicated in lung small cell carcinoma. Orthologous to human CHRNA9 (cholinergic receptor nicotinic alpha 9 subunit). PHENOTYPE: Homozygous mutation of this gene results in abnormal innervation of the outer hair cells and depressed olivocochlear response. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
