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Allele : Psmc5<tm1.1Genp> protease (prosome, macropain) 26S subunit, ATPase 5; targeted mutation 1.1, Gentry N Patrick
Primary Identifier  MGI:7506899 Allele Type  Targeted
Attribute String  Not Specified Gene  Psmc5
Transmission  Germline Strain of Origin  (C57BL/6 x 129S/SvEv)F1
Is Recombinase  false Is Wild Type  false
molecularNote  Serine codon 120 (AGC) in exon 5 was changed to aspartic acid (GAC) (p.S120D) and an FRT site flanked neomycin resistance gene cassette was inserted into intron 3. The neo cassette was removed through subsequent Flp-mediated recombination. The mutation turns the affected residue in the encoded peptide from phosphorylatable to a phosphomimetic.
  • mutations:
  • Nucleotide substitutions
  • synonyms:
  • Rpt6 S120D,
  • Rpt6 S120D
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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Trail: Allele




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