| First Author | Lalanne JL | Year | 1985 |
| Journal | Cell | Volume | 41 |
| Issue | 2 | Pages | 469-78 |
| PubMed ID | 3838699 | Mgi Jnum | J:20087 |
| Mgi Id | MGI:68200 | Doi | 10.1016/s0092-8674(85)80020-9 |
| Citation | Lalanne JL, et al. (1985) Expression of class I genes in the major histocompatibility complex: identification of eight distinct mRNAs in DBA/2 mouse liver. Cell 41(2):469-78 |
| abstractText | The mouse H-2 multigene family includes the genes coding for the major transplantation antigens and for genes located in the Qa-TIa region. We have studied a collection of class I cDNA clones made from liver mRNA of DBA/2 mice (H-2d haplotype) and found that at least six distinct class I genes are transcribed, including three genes of the Qa-TIa region. Two of these six genes each yield two distinct mRNAs, resulting from alternate splicing. Altogether, liver cells may express at least eight distinct class I polypeptides, of which three might be secreted, while one may be a new presumptive nonpolymorphic surface antigen. |
