| First Author | Cai W | Year | 1996 |
| Journal | Immunogenetics | Volume | 45 |
| Issue | 2 | Pages | 97-107 |
| PubMed ID | 8952959 | Mgi Jnum | J:37997 |
| Mgi Id | MGI:85390 | Doi | 10.1007/s002510050177 |
| Citation | Cai W, et al. (1996) Sequence and transcription of Qa-2-encoding genes in mouse lymphocytes and blastocysts. Immunogenetics 45(2):97-107 |
| abstractText | The protein product of the mouse preimplantation embryo development (Ped) gene, which controls the rate of preimplantation embryonic cleavage division and subsequent embryo survival, is the Qa-2 antigen. This major histocompatibility complex (MHC) class I b protein is encoded by four genes, Q6, Q7, Q8, and Q9. The present study was undertaken to begin to elucidate which of the four Qa-2-encoding genes are responsible for the Ped gene phenotype in the C57BL/6 mouse (H2(b)). First, restriction maps of the four genes, using 25 restriction enzymes, were created. The RE maps confirmed that Q6 is similar to Q8 and Q7 is similar to Q9, but that the Q6/Q8 gene pair differs from the Q7/Q9 gene pair. The genomic DNA sequences of Q6 and Q8 were |
