| Primary Identifier | MGI:1343166 | Organism | mouse, laboratory |
| Chromosome | 7 | NCBI Gene Number | 19144 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0) Predicted to enable serine-type endopeptidase activity. Predicted to be involved in positive regulation of G protein-coupled receptor signaling pathway and regulation of neuron projection development. Is active in cornified envelope. Is expressed in several structures, including brain. Human ortholog(s) of this gene implicated in Alzheimer's disease; Lewy body dementia; Parkinson's disease; demyelinating disease; and multiple system atrophy. Orthologous to human KLK6 (kallikrein related peptidase 6). PHENOTYPE: Mice homozygous for a knock-out allele exhibit decreased mature oligodendrocytes in the developing spinal cord. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
