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Protein Coding Gene : E2f8 E2F transcription factor 8

Primary Identifier  MGI:1922038 Organism  mouse, laboratory
Chromosome  7 NCBI Gene Number  108961
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Enables DNA binding activity; DNA-binding transcription repressor activity; and identical protein binding activity. Involved in several processes, including hepatocyte differentiation; regulation of cell cycle process; and trophoblast giant cell differentiation. Acts upstream of or within fibroblast proliferation. Located in nucleus. Is expressed in central nervous system and retina. Orthologous to human E2F8 (E2F transcription factor 8).
PHENOTYPE: Mice homozygous for a knock-out allele develop normally through puberty and live to old age. [provided by MGI curators]
  • synonyms:
  • AA410048,
  • RIKEN cDNA 4432406C08 gene,
  • MGI:2141825,
  • E2f8,
  • expressed sequence AA410048,
  • E2F transcription factor 8,
  • 4432406C08Rik

Features --> Cross References

Genome

Sequence Feature Displayer

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

0 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

6 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For