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Allele : Srf<tm1Rjs> serum response factor; targeted mutation 1, Robert J Schwartz

Primary Identifier  MGI:3604097 Allele Type  Targeted
Gene  Srf Transmission  Germline
Strain of Origin  129S7/SvEvBrd-Hprt1<b-m2> Is Recombinase  false
Is Wild Type  false
molecularNote  Sequence encoding the DNA binding and dimerization domains of the protein was replaced by the insertion of an NLS-betagalactosidase-neomycin cassette. In situ hybridization demonstrated expression in embryos ranging from E7.5 to E9.5 predominantly in the cardiac crescent and later in the heart tube, the somites, and the precondensed mesenchyme in the tail, consistent with the expression of the endogenous gene.
  • mutations:
  • Insertion
  • synonyms:
  • SRF<->,
  • SRF<LacZ>,
  • SRF<LacZ>,
  • SRF<->
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

6 Publication categories

Trail: Allele